Question 1

what can ido if bloodwork shows marked polyclonal hypergammaglobulinemia?? i don't have apt with liver specialist until june...

Accepted Answer

Best thing to do is-: nothing until you have a diagnosis.  Polyclonal hypergammaglobulinemia is non specific and simply indicates the immune system is activated.  This is normal with many infectious and inflammatory diseases.  It does not need to be treated per se and bears little relationship to the severity of the underlying disease.  It will resolve when the underlying disease resolves.

Question 2

recent bloodwork for ig. my igg is elevated to1950 on 1650 scale, total protein normal range. mild hypergammaglobulinemia  polyclonal?

Accepted Answer

Stop worrying: You may be getting over a mild infection. Polyclonal elevations of IgG are common and never worth worrying about. If you have some other illness, this is a tip in diagnosing and following you. Otherwise, relax and keep an eye on how you actually feel.

Question 3

causes of hypergammaglobulinemia?

Accepted Answer

Mono or Polyclonal: High levels of immunoglobulins (hypergammaglobulinemia) can be monoclonal (specific) - due to malignant proliferation of plasma cells or lymphocytes as in myeloma or waldenstrom's macroglobulinemia. Polyclonal (many types) hypergammaglobulinemia is a benign condition due to infection, inflammation causing non-specific gamma globulin production such as in hepatitis, immune and allergic disorders.

Question 4

can you tell me about immunity and i am having a difficult time with finding information on hypergammaglobulinemia. so my question is what is it?

Accepted Answer

Low IgG: Immunoglobulins are a type of protein made by your body to help protect it against infections.  There are five types of immunoglobulins: IgA, IgD, IgE, IgG, and IgM.  Each of these has a slightly different function in infection fitting.  Hypogammaglobulinemia refers to low levels of IgG the primary infection fighting antibody.  The most common form in adults is common variable immune deficiency.

Question 5

mild polyclonial hypergammaglobulinemia found on protien test. could it be cancer?

Accepted Answer

: It is a nonspecific finding, not a typical finding in any cancer. We are more concerned about hyperglobulinemia with monoclonal type, i.e. monoclonal gammopathy.

Question 6

ra factor,ana positive with polyarthritis accp negative and polyclonal hypergammaglobulinaemia. whats the diagnosis?

Accepted Answer

Auto immune disorder: The information you provided is not sufficient to provide a specific diagnosis. It suggest an auto-immune inflammatory disorder. All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that.

Question 7

what does polyclonal n biclonal bands mean ?

Accepted Answer

Multiple and 2: Polyclonal means there are at least several. Biclonal means there are two.

Question 8

how does hiv cause polyclonal cell activation?

Accepted Answer

B-cells: The ways in which HIV and hiv-infected immune cells cause overgrowth of uninfected b-cells, making them divide (polyclonal) and overfunction (polyclonal gammopathy, b-cell quasi-lymphomas) are coming to be known and are hugely complex. Best recent review http://www.Nature.Com/nri/journal/v9/n4/execsumm/nri2524.Html.

Question 9

what is mild polyclonal gammopathy that's what the dr said i have but i haven't seen him yet?

Accepted Answer

Means little alone: You have more antibodies on board than most people. Maybe you're just getting over an illness, or it's your celiac disease, or it's just you. This is meaningful only as part of a workup for other illness.

Question 10

what does this mean;  an oligoclonal result is indicative of the presence of several distinct tcr-gamma amplicons that may represent a low-level t-cell clone in a polyclonal t-cell background or a true oligoclonal t-cell expansion.?

Accepted Answer

: Ask the physician who ordered the test. Good Luck

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Doctor answers about:

Polyclonal hypergammaglobulinemia

A member asked:

What can ido if bloodwork shows marked polyclonal hypergammaglobulinemia?? i don't have apt with liver specialist until june...

A member asked:

Recent bloodwork for ig. my igg is elevated to1950 on 1650 scale, total protein normal range. mild hypergammaglobulinemia polyclonal?

A member asked:

Causes of hypergammaglobulinemia?

A member asked:

Can you tell me about immunity and i am having a difficult time with finding information on hypergammaglobulinemia. so my question is what is it?

A member asked:

Mild polyclonial hypergammaglobulinemia found on protien test. could it be cancer?

A member asked:

Ra factor,ana positive with polyarthritis accp negative and polyclonal hypergammaglobulinaemia. whats the diagnosis?

A member asked:

What does polyclonal n biclonal bands mean ?

A member asked:

How does hiv cause polyclonal cell activation?

A member asked:

What is mild polyclonal gammopathy that's what the dr said i have but i haven't seen him yet?

A member asked:

What does this mean; an oligoclonal result is indicative of the presence of several distinct tcr-gamma amplicons that may represent a low-level t-cell clone in a polyclonal t-cell background or a true oligoclonal t-cell expansion.?

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