Question 1

what are the signs and symptoms of multiple myeloma?

Accepted Answer

CRAB +: C - hypercalcemia
r - renal (kidney) disease, elevated crt
a - anemia (not explained by other causes)
b - bone disease - eg osteoporosis, fractures, or lytic (moth eat) lesions

+ neuropathy, frequent infections, etc...

Question 2

very good afternoon doctors. are there any typical or telltale signs of renal kidney multiple myeloma or renal kidney amloydisis? are there symptoms to rule these conditions in or to rule them out?

Accepted Answer

: There are no typical symptoms to indicate either. Both can affect the kidney function in later stages  and manifest signs of kidney failur

Question 3

need doctor's help! will itching be a sign of multiple myeloma?

Accepted Answer

I seriously doubt it: I cannot say I have ever seen a patient with this association.

Question 4

is multiple myeloma hereditary?

Accepted Answer

Not generally...: Myeloma and other hematologic malignancies are not generally considered "hereditary"/familial, but some are. Risk in family members is around 2x risk of population.
An nci study is characterizing:

screening individuals and families at high risk for hematologic cancers

nct00052234

http://clinicaltrials.Gov/ct2/show/nct00052234?Term=nct00052234&rank=1.

Question 5

how common is multiple myeloma?

Accepted Answer

1% : 1% of all cancers.
2nd most common hematologic malignancy.
A great nci snapshot link:
http://www.Cancer.Gov/aboutnci/servingpeople/snapshots/myeloma.Pdf.

Question 6

what other tests for multiple myeloma?

Accepted Answer

Myeloma tests: There are many tests that are used to diagnose and stage multiple myeloma.  These can include: cbc, chemistry panel, bone marrow biopsy, chromosome studies, plain xrays of the bones, 24 hour urine collection.  Sometimes special imaging studies such as mri, ct or pet may be used.

Question 7

what are the causes of multiple myeloma?

Accepted Answer

Unknown/MGUS: The exact cause of multiple myeloma is not known.
Myeloma is almost always (?Always) preceded by monoclonal gammopathy of undetermined significance (mgus).

Risks: age, male gender, black race; radiation, benzene/petroleum exposure

laboratory studies can help predict risk of conversion from mgus to myeloma.

Question 8

what is the symptoms for multiple myeloma?

Accepted Answer

MM: Fatigue, bone pain, fractures of bones without injury, night sweats, pallor, malaise. Other than bone fractures, the other symptoms are not very specific.

Question 9

what is multiple myeloma a risk factor for?

Accepted Answer

Multiple myeloma can lead to::   Acute tubular necrosis, Aspergillosis, Acute kidney failure, Kidney failure, Pancytopenia.

Question 10

could multiple myeloma be treated and cured?

Accepted Answer

Yes: Multiple myeloma can certainly be treated. There a variety of new drugs available. We are likely curing some myeloma patients, but we don't necessarilyl know who these peopple are when we start treatment. Check out the #mmsm tweetchat including an upcoming topic of myeloma cure.

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Doctor answers about:

Multiple myeloma signs

A member asked:

What are the signs and symptoms of multiple myeloma?

A member asked:

Very good afternoon doctors. are there any typical or telltale signs of renal kidney multiple myeloma or renal kidney amloydisis? are there symptoms to rule these conditions in or to rule them out?

A member asked:

Need doctor's help! will itching be a sign of multiple myeloma?

A member asked:

Is multiple myeloma hereditary?

A member asked:

How common is multiple myeloma?

A member asked:

What other tests for multiple myeloma?

A member asked:

What are the causes of multiple myeloma?

A member asked:

What is the symptoms for multiple myeloma?

A member asked:

What is multiple myeloma a risk factor for?

A member asked:

Could multiple myeloma be treated and cured?

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