Question 1

are metastasis and metastases synonymous?

Accepted Answer

Singular/pleurals: Used for one metastasis or more metastases!

Question 2

what are visceral metastases exactly ?

Accepted Answer

Cancer in organs: Metastases, or areas of cancer spread, to the liver, lungs, or other organs in the body.  Metastases to bone are not visceral metastases.

Question 3

what are the causes of  hepatic metastases?

Accepted Answer

Hepatic mets: I think you mean what cancers can cause hepatic mets. It usually happens when cancer spread through blood circulation in liver. Many different type of cancer can spread to liver. Most commonly colon, any cancer of digestive system and lung cancer. But mostly any cancer can spread to liver.

Question 4

how to differentiate primary tumor cells from cells of metastases?

Accepted Answer

Close exam: primary tumor cells are well defined, arising in the organ that initiates the lesion.  A cancer of the breast when biopsied shows adenoca cells of breast origin.  When metastatic to liver or lung, biopsy will show the same cells as the primary .  If the lesion arises in the liver it is not metastatic in terms of cells seen but liver tumor cells or hepatoma.

Question 5

please explain reasons why whipple resection contraindicated with metastases?

Accepted Answer

No survival: Pancreas cancer has a poor prognosis.  No survival noted if performed in the presence of metastatic disease.  Use of chemotherapy such as gemcitabine and Abraxane give the best chance for prolonged survival in terms of months after diagnosis made.  
Only 10% or patients diagnosed with pancreatic head cancer are candidates for a whipple resection, and even here only 10% of patients are ned at 2 yrs.

Question 6

what are the areas of infiltrative metastases for oral low-grade adenocarcinoma?

Accepted Answer

Submax region: Oral low grade adenocarcinomas are relatively rare.  Since the major portion of the oral cavity is squamous cells lining the cavity, squamous Ca is most frequently found.  The adenocarcinomas arising from glandular tissue arise from the minor salivary gland lining the cheeks  and areas like sublingual glands which when harboring malignancies, spread is to the upper cerival or submax region.

Question 7

i was wondering what are the most common areas of infiltrative metastases for oral low-grade adenocarcinoma?

Accepted Answer

Unclear: Your question is not clear to me. Please expand and explain it better. Most oral cancers spread to the upper neck lymph nodes.

Question 8

describe the features of metastases to the bone.?

Accepted Answer

Varies: Bone metastases features can vary. Some are bone "lytic" (moth eaten) such as squamous cell cancers or multiple myeloma. Others are "blastic" such as breast, prostate, etc. Symptoms vary from asymptomatic to painful. Bones may easily (pathologically) fracture. Treatment can include bone directed therapy such as bisphosphonates, xgeva (denosumab), radiation, radio frequency ablation, v-plasty.

Question 9

is nano
knife ( ablation ) worth doing for 3 /4 metastases all
under 2 cm?

Accepted Answer

Oncology : The nano knife has been FDA approved in 2009 for the surgical ablation of soft tissue, however it has not been approved to treat other specific diseases or conditions. With metastatic cancer your case sounds more complex and worthy of clinical trial status so it is best to consult with your treating oncologist. Be well:)

Question 10

is sirt worth doing for liver liver metastases

1x 7 cm
1x 6 cm
8 under 2 cm?

Accepted Answer

Yes: Multiple liver lesions can be treated by a number of approaches because what is in liver   will not spread. Originally ligation of hepatic artery was used since portal vein supplies hepatocytes and hepatic artery the metastatic tumors.Can be used with SIRT which is a form of RT treatment wherein a dose  of SIR-Spheres® microspheres are delivered up to 40 times higher than conventional doses.

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Doctor answers about:

Metastasis vs metastases

A member asked:

Are metastasis and metastases synonymous?

A member asked:

What are visceral metastases exactly ?

A member asked:

What are the causes of hepatic metastases?

A member asked:

How to differentiate primary tumor cells from cells of metastases?

A member asked:

Please explain reasons why whipple resection contraindicated with metastases?

A member asked:

What are the areas of infiltrative metastases for oral low-grade adenocarcinoma?

A member asked:

I was wondering what are the most common areas of infiltrative metastases for oral low-grade adenocarcinoma?

A member asked:

Describe the features of metastases to the bone.?

A member asked:

Is nano knife ( ablation ) worth doing for 3 /4 metastases all under 2 cm?

A member asked:

Is sirt worth doing for liver liver metastases 1x 7 cm 1x 6 cm 8 under 2 cm?

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