Question 1

when testing for antiphospolipid antibody syndrome,  does taking baby aspirin affect the lupus anticoagulant (ptt-la, drvvt) test results?

Accepted Answer

It should not: The aspirin inhibits platelets not other parts of the clotting cascade.

Question 2

what is the definition or description of: lupus anticoagulant antibodies present?

Accepted Answer

Depends: The lupus anticoagulant (la) is a screening test for anti-phospholipid antibody syndrome. (apas). Apas includes sometimes severe  blood clotting of the arteries and veins. Women with apas sometimes have multiple miscarriages. Some but not all apas patients have lupus (sle). There are false positive la tests: infection and if the test is taken when patient is on an anti-coagulant such as heparin.

Question 3

what is the definition or description of: lupus anticoagulant antibodies?

Accepted Answer

See below: Lupus anticoagulant (la) is an immunoglobulin that binds to phospholipids and proteins associated with the cell membrane. The disease name is a misnomer. La is actually a prothrombotic agent. The presence of la antibodies precipitates the formation of thrombi. The name derives from their properties in vitro, since in lab tests la causes an increase in clotting time.

Question 4

i have lupus anticoagulant antibodies. do i need to worry if i am on coumadin (warfarin)?

Accepted Answer

Coumadin (warfarin) works well!: The cascade of potential thrombosis mechanisms usually caused by acla -f the IgG or IgM class, is virtually blunted the coumadin (warfarin).
So little to worry about, providing someone is checking your protime and inr, to make sure you are in therapeutic range. Heparin and it's newer analogues may work better, but require injection.

Question 5

i have lupus anticoagulant antibodies (aps). do i need to worry about bein on coumadin (warfarin)?

Accepted Answer

No: You should be on Coumadin (warfarin) to prevent clots.

Question 6

if i have mixed connective tissue disorder with the lupus anticoagulant antibody can i take nsaids?

Accepted Answer

Yes: The real question is should you be on long term anticoagulation. If you have had a pulmonary embolis, stroke or heart attack, the answer is usually yes andyou might need to treat simultaneously with aspirin, coumadin(rat poiison) and heparin.  Sometimes a very tough disease tocontrol.

Question 7

is it a bad idea to be on coumadin (warfarin) if i have lupus anticoagulant antibodies (aps)?

Accepted Answer

No: People with lupus anti coagulant can get blood clots and Coumadin (warfarin) is used to prevent them.

Question 8

i miscarried twice. doc advised me to do thrombophilia screen, anticardiopin antibody and lupus anticoagulant - what are they?

Accepted Answer

Tests for clotting: These are tests for abnormal clotting factors that, if present, may be causing you to miscarry. Someone of these causes can be treated during pregnancy.

Question 9

i have a positive ana, positive lupus anticoagulant, 386 value for microsomal antibodies. c3 of 113, c4 of 53.  a rash on face could it be lupus?

Accepted Answer

Yes: Lupus is a major consideration. The microsomal antibodies suddest that autoimmune thyroid disease is also present. See a rheumatologist if you have done so already.

Question 10

is my bruising, burning/stinging at injection site normal-am i doing something wrong? lupus anticoagulant antibody disorder-history of dvt and pe's.43 yrs old.have been on new subq enoxaparin-100mg/ml twice daily for 3 days.pain lasts at least an hour, ha

Accepted Answer

I : I am very concerned about your symptoms.  Please call your hematologist immediately and discuss these symptoms.  They could represent an unusual reaction or could represent that you are over-anticoagulated.  Please call immediately.  If you develop any shortness of breath, bleeding, or new symptoms then please be seen in the er.

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Doctor answers about:

Lupus anticoagulant antiphospholipid antibody

A member asked:

When testing for antiphospolipid antibody syndrome, does taking baby aspirin affect the lupus anticoagulant (ptt-la, drvvt) test results?

A member asked:

What is the definition or description of: lupus anticoagulant antibodies present?

A member asked:

What is the definition or description of: lupus anticoagulant antibodies?

A member asked:

I have lupus anticoagulant antibodies. do i need to worry if i am on coumadin (warfarin)?

A member asked:

I have lupus anticoagulant antibodies (aps). do i need to worry about bein on coumadin (warfarin)?

A member asked:

If i have mixed connective tissue disorder with the lupus anticoagulant antibody can i take nsaids?

A member asked:

Is it a bad idea to be on coumadin (warfarin) if i have lupus anticoagulant antibodies (aps)?

A member asked:

I miscarried twice. doc advised me to do thrombophilia screen, anticardiopin antibody and lupus anticoagulant - what are they?

A member asked:

I have a positive ana, positive lupus anticoagulant, 386 value for microsomal antibodies. c3 of 113, c4 of 53. a rash on face could it be lupus?

A member asked:

Is my bruising, burning/stinging at injection site normal-am i doing something wrong? lupus anticoagulant antibody disorder-history of dvt and pe's.43 yrs old.have been on new subq enoxaparin-100mg/ml twice daily for 3 days.pain lasts at least an hour, ha

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