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is sickle cell anemia dominant or recessive trait

A 53-year-old member asked:
Dr. Caren Reaves
23 years experience Obstetrics and Gynecology
Autosomal recessive: It is recessive, meaning a person has to inherit a gene for ss from each parent to be affected, but it is not sex linked.

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A 48-year-old member asked:
Dr. Scott Diede
28 years experience Pediatric Hematology and Oncology
25% chance: If both parents have trait, then the child has a 25% chance of having sickle cell disease, a 50% chance of having trait, and a 25% chance of not inher ... Read More
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A 48-year-old member asked:
Dr. Martin Rubenstein
44 years experience Hematology and Oncology
Usually none.: Patients with sca trait usually have no symptoms. If they are in an environment where oxygen is low, like high altitude, it is possible to have a pai ... Read More
A 28-year-old female asked:
Dr. John Munshower
29 years experience Family Medicine
Usually not: Sickle cell trait is a hemoglobin genotype as and is generally regarded as a benign condition. However, individuals with sickle cell trait may have ra ... Read More
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A 56-year-old member asked:
Dr. Steven Ginsberg
36 years experience Hematology and Oncology
Inherited: Sickle cell anemia is an inherited, non-sex linked genetic mutation ( actually several mutations) that leads to the formation of an abnormal hemoglobi ... Read More
A 38-year-old member asked:
Dr. Craig MacArthur
33 years experience Pediatric Hematology and Oncology
Dominant genetically: Sickle cell disease is inherited as an autosomal recessive condition, which is what you will read from online sources and textbooks. One must inherit ... Read More
A 46-year-old member asked:
Dr. Ankush Bansal
16 years experience Internal Medicine
Recessive: Sickle cell is autosomal recessive which means both parents must have a copy of the defective allele (one or both can be carriers but exhibit no sympt ... Read More
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A 45-year-old member asked:
Dr. Michele Lambert
21 years experience Pediatric Hematology and Oncology
basically yes: The mutation that causes sickle cell disease is a recessive mutation in that you need two copies of the changed gene to have the disease (or one copy ... Read More
A 46-year-old member asked:
Dr. Ankush Bansal
16 years experience Internal Medicine
Yes: Sickle cell anemia is due to a genetic mutation in the dna that encodes for the hemoglobin molecule. Thus, it is hereditary.
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A 40-year-old member asked:
Dr. Robert Kwok
32 years experience Pediatrics
Neither: People normally have 2 beta globulin genes. A mutation in one or both genes leads to 3 levels of beta thalassemia. The genetics of the disorder is not ... Read More
A 41-year-old member asked:
Dr. Martin Rubenstein
44 years experience Hematology and Oncology
Hemoglobinopathy: Patients with sickle cell anemia make an abnormal hemoglobin (hgb.). Normal HGB consists of paired protein chains (globin) and an iron containing par ... Read More
A 45-year-old member asked:
Dr. James Ferguson
45 years experience Pediatrics
Yes: The recessive sickle gene is carried silently in a percentage of the population.When two carriers produce offspring their is 25% risk with each concep ... Read More
A 50-year-old member asked:
Dr. Michael Engel
19 years experience Pediatric Hematology and Oncology
If you mean....: Is the beta globin gene transmitted on a sex chromosome (either x or y), the answer is no. The beta globin locus is autosomal, and classical sickle c ... Read More
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A 37-year-old member asked:
Dr. Joseph Torkildson
38 years experience Pediatric Hematology and Oncology
11: The beta globin gene is mutated in sickle cell anemia; it is located on chromosome 11.
A member asked:
Dr. Christian Pariseau
19 years experience Pediatrics
Recessive, but: complicated http://thalassemia.com/genetics-inheritance.aspx
A 29-year-old female asked:
Dr. Le Wang
Dr. Le Wang answered
35 years experience Internal Medicine
Most less severe: Most are less severe in sickle cell thalassemia, but depends. HbS/B(0)thal: similar to HbSS in severity maybe slightly less severe. HbS/B(+)thal: has ... Read More
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A 42-year-old member asked:
Dr. Steven Ginsberg
36 years experience Hematology and Oncology
Genes: Sickle cell anemia occurs when someone has 2 sickle cell genes. Normal hemoglobin (hb) genes code for hb a. A sickle cell gene codes for hb s. Having ... Read More
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A 47-year-old member asked:
Dr. Maulik Shah
23 years experience Clinical Genetics
Carrier vs. Affected: Sickle cell trait denotes being a carrier while sickle cell disease is someone who has the disorder. Sickling requires 2 genes. A person with the s ... Read More
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A 30-year-old member asked:
Dr. Jay Park
Dr. Jay Park answered
49 years experience Pediatrics
Chromosome No. 11: Point mutation at beta-globin gene located at chromosome no. 11 results in production of defective hemoglobin, sickle hemoglobin.
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A 43-year-old member asked:
Dr. Joseph Torkildson
38 years experience Pediatric Hematology and Oncology
I Don't Think So: I'm guessing a bit as to what you mean by your question. Sickle cell anemia is caused by a gene mutation on both copies of the beta globin gene. In th ... Read More
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A 47-year-old member asked:
Dr. James Ferguson
45 years experience Pediatrics
Neither: Leukemia has a variety of factors of influence;however,it is not inherited as a simple autosomal recessive or dominant trait.
A 48-year-old member asked:
Dr. James Ferguson
45 years experience Pediatrics
Yes: Or one with trait and one with ss.
A 55-year-old member asked:
Dr. Scott Diede
28 years experience Pediatric Hematology and Oncology
No: Sickle cell trait is when a person has one mutated copy of the beta-hemoglobin gene and one normal copy. You always inherit the mutated hemoglobin fro ... Read More

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