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is myelofibrosis hereditary

A 37-year-old male asked:
Dr. Ed Friedlander
43 years experience in Pathology
Almost never: Common myelofibrosis and its cousin myeloid metaplasia are almost always sporadic. There are a few genetic marrow-failure syndromes but these are fair ... Read More
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A 43-year-old member asked:
Dr. Aasim Sehbai
23 years experience in Hematology and Oncology
Myelofibrosis: A blood disorder which usually affects the bone marrow causing anemia and low counts, and cause spleen enlargement and other constitutional symptoms l ... Read More
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A 34-year-old female asked:
Dr. Martin Rubenstein
44 years experience in Hematology and Oncology
Stem cell damage. : Myelofibrosis is associated with damage to dna of bone marrow stem cells. This results in abnormal growth and functioning of these cells. The most com ... Read More
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A 38-year-old member asked:
Dr. Aasim Sehbai
23 years experience in Hematology and Oncology
Myelofibrosis: Difficult disease to fix, if can be managed. Young patients bone marrow or stem cell transplant is an option.
A 54-year-old member asked:
Dr. Martin Rubenstein
44 years experience in Hematology and Oncology
Danazol perhaps?: Myelofibrosis (mf) is a blood condition where the bone marrow is replaced by scar tissue (fibrosis). One problem that develops is anemia. Medication ... Read More
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A 41-year-old member asked:
Dr. Christian Schultheis
23 years experience in Hematology and Oncology
Depends: They are several phases of the disease and it depends on how much fibrosis is present in the marrow. Since this is included in the group of disorders ... Read More
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4 thanks
A 47-year-old member asked:
Dr. Liawaty Ho
22 years experience in Hematology and Oncology
Pmf: A condition where there is a significant and uncontrolled growth/increase of reticulin fibre inside thebone marrow resulting in decrease production ... Read More
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A 51-year-old member asked:
Dr. Liawaty Ho
22 years experience in Hematology and Oncology
Not in early phase: In very early phase you do not usually have noticeable symptoms. When it is progressing- you are going to start noticing more symptoms.
A 39-year-old member asked:
Dr. Steven Ginsberg
36 years experience in Hematology and Oncology
Males: Males are more affected by myelofibrosis. About 2/3 of people affected are male.
A 67-year-old male asked:
Dr. Amandeep Kaur
9 years experience in Family Medicine
Possible: Although not very commonly but yes it can be familial as well. If it occurs during childhood then there may be a congenital/chromosomal abnormality as ... Read More
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