A member asked:

What is myelofibrosis?

A doctor has provided 1 answer
Dr. Aasim Sehbai answered

Specializes in Medical Oncology

Myelofibrosis: A blood disorder which usually affects the bone marrow causing anemia and low counts, and cause spleen enlargement and other constitutional symptoms like weight loss, malaise, risk of infection and bleeding. It can lead to leukemia or a bone marrow failure syndrome. Bone marrow transplant in young patients can be considered. Jakafi (ruxolitinib) is a new drug approved to treat symptoms of myelofibrosis.

Answered 10/13/2016

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