A 35-year-old member asked:
What is myelofibrosis?
1 doctor answer • 1 doctor weighed in

Dr. Aasim Sehbaianswered
Medical Oncology 26 years experience
Myelofibrosis: A blood disorder which usually affects the bone marrow causing anemia and low counts, and cause spleen enlargement and other constitutional symptoms like weight loss, malaise, risk of infection and bleeding. It can lead to leukemia or a bone marrow failure syndrome. Bone marrow transplant in young patients can be considered. Jakafi (ruxolitinib) is a new drug approved to treat symptoms of myelofibrosis.
Created for people with ongoing healthcare needs but benefits everyone.
5.5k viewsAnswered >2 years ago
Similar questions
A 46-year-old member asked:
Is danogal for myelofibrosis?
1 doctor answer • 2 doctors weighed in

Dr. Martin Rubensteinanswered
Hematology and Oncology 47 years experience
Danazol perhaps?: Myelofibrosis (mf) is a blood condition where the bone marrow is replaced by scar tissue (fibrosis). One problem that develops is anemia. Medications related to testosterone (androgens) sometimes help. Danazol is one such drug. It has many other uses. Other drugs for mf include jak2 inhibitors, thalidomide derivatives, epoietin and hydroxyurea.
Created for people with ongoing healthcare needs but benefits everyone.
5.7k viewsReviewed >2 years ago
Australia
A 32-year-old female asked about a 31-year-old male:
Is myelofibrosis. Hereditary?
1 doctor answer • 1 doctor weighed in

Dr. Ed Friedlanderanswered
Pathology 46 years experience
Almost never: Common myelofibrosis and its cousin myeloid metaplasia are almost always sporadic. There are a few genetic marrow-failure syndromes but these are fairly easy to recognize.
Created for people with ongoing healthcare needs but benefits everyone.
3.7k viewsAnswered >2 years ago
Last updated Oct 13, 2016
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