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Interesting facts about trisomy 18

A 36-year-old member asked:
Dr. Nikolaos Zacharias
Maternal-Fetal Medicine 27 years experience
Genetic accident.: Trisomy 18 is a generally perinatally lethal (few exceptions prove the rule) genetic aberration that occurs when chromosomal non-disjunction occurs in... Read More
Dr. James Ferguson
Pediatrics 47 years experience
Error in formation: During the formation of the egg or sperm, the chromosome(c) pairs split with one of each going to the egg or sperm. At conception, the egg & sperm ea... Read More
A 30-year-old member asked:
Dr. Gregory Mosolf
Pediatrics 26 years experience
Extra chromosome: In trisomy 18 the patient has an extra chromosome 18. This genetic disorder frequently causes heart and kidney defects. They may have a small head an... Read More
Dr. Heidi Fowler
Psychiatry 26 years experience
Edwards Syndrome: Trisomy 18 - chromosomal condition in 1/5,000 to 6,000 live births due to random events while egg or sperm form.Usually not inherited. 5 to 10% live p... Read More
A 44-year-old member asked:
Dr. James Ferguson
Pediatrics 47 years experience
Chromosome study: Most trisomy 18's arise as a new error on meiosis during the formation of a womans egg.It is not "carried" like a sickle trait. There is a rare possib... Read More
Dr. Heidi Fowler
Psychiatry 26 years experience
Trisomy 18: Partial Trisomy 18 can be inherited from someone who has no signs of Trisomy 18. These people do not have an extra chromosome 18 – instead genetic mat... Read More
A 30-year-old member asked:
Dr. James Ferguson
Pediatrics 47 years experience
Keep them comfortabl: These patients are supported with comfort measures as much as possible. Fluids, nutrition, oxygen, etc.As a universally fatal disorder, management fo... Read More
A 35-year-old member asked:
Dr. Gregory Mosolf
Pediatrics 26 years experience
Extra chromosome: In trisomy 18 the patient has an extra chromosome 18. This genetic disorder frequently causes heart and kidney defects. They may have a small head an... Read More
A 43-year-old member asked:
Dr. Golder Wilson
Specializes in Clinical Genetics
Translocation: If the edwards syndrome infant has translocation (joining of chromosomes) rather than a free-standing extra 18 chromosome (trisomy), then the parent m... Read More
A 45-year-old member asked:
Dr. Craig Uhl
Pediatrics 28 years experience
Trisomy18.org: There is a foundation set up for this syndrome - go to http://www.Trisomy18.Org.
A 35-year-old member asked:
Dr. James Ferguson
Pediatrics 47 years experience
Confusing question: Are you saying you have T18, or your pregnancy is positive for T18. The first response would not be possible. The second is worrisome. Those with any ... Read More
A 38-year-old member asked:
Dr. Karl Muench
Clinical Genetics 62 years experience
Almost zero: Trisomy 18 (edwards syndrome) is caused by the spontaneous, accidental inclusion of an extra chromosome #18 in the zygote for a total of three. Your s... Read More
A 42-year-old member asked:
Dr. Ankush Bansal
Internal Medicine 18 years experience
Maybe: This is complicated. First, in most cases, there is an extra chromosome in all cells so the sperm and eggs will be genetically defective anyways & so ... Read More