Question 1

what are the tests for factor viii deficiency?

Accepted Answer

Blood tests and: Family history.  Blood tests for levels of factor viii are available, though simpler tests, e.g., PTT with appropriate family history may be sufficient.

Question 2

what sort of disorder is factor viii deficiency?

Accepted Answer

Hemophilia: Factor viii deficiency is classical hemophilia that affected royal families of europe.  It leads bleeding in tissue, especially in joints.  It is an x-linked disease and manifests essentially only in men, women are carriers.

Question 3

what are the symptoms of factor viii deficiency?

Accepted Answer

Bleeding: Factor viii is one of the coagulation factors and its deficiency is the cause of hemophilia a.  Depending on the severity of deficiency, there may be no symptoms, bleeding from cuts and excessive bruising with minor trauma, bleeding into joints, excessive bleeding due to surgery, including circumcision.

Question 4

what is a successful cure of hemophilia(factor viii deficiency).?

Accepted Answer

None: Hemophilia is treated with recombinant factor viii, however, it is not a cure.

Question 5

is it possible to have a factor viii deficiency and not have actual hemophilia?

Accepted Answer

Not really: Factor viii deficiency will cause hemophilia.

Question 6

what is the treatment for factor viii deficiency?

Accepted Answer

Factor VIII: Concentrate.  Factor viii is prepared by recombinant technology, though it may also be extracted from human plasma.  Depending on the severity of deficiency, factor viii may be given prophylactically or to treat episodes of bleeding.  The drug is given intravenously.

Question 7

can you tell me if someone is heterozygous w/ the hemophilia gene, is it possible for them to still have factor viii deficiency?

Accepted Answer

Yes, in men: Hemophilia is a sex linked disorder and men develop the disease when there only x chromosome has the defective gene. See this site for more info.
http://www.nlm.nih.gov/medlineplus/ency/article/000538.htm.

Question 8

what are two blood abnormalities from factor 8?

Accepted Answer

I am not sure: I understand the question.  Factor viii deficiency from birth is a form of hemophilia.  It is also possible to develop an acquired inhibitor of factor viii which also is associated with life threatening bleeding.

Question 9

would someone with antiphospholipid syndrome have an increase of factor 8?

Accepted Answer

Usually NOT: The mechanism of increased clotting in antiphospholipid syndrome (aps) is complex involving many levels of the clotting cascade. Although a paradoxical prolongation of the prothrombin or thromboplastin time is seen in the lab test (blood looks thinner), what happens inside the body could be the opposite - an increased risk of clotting that has nothing to do with levels of factor 8.

Question 10

what does a 162 level of factor 8 mean?  lab where tested said normal range was 50-150. please advise.

Accepted Answer

Higher risk of clots: Many factors influence the levels of factor 8 in the body, some of them most likely put someone at a higher risk of developing blood clots, both arterial and venous. Many studies have shown that factor 8 levels above 150 are correlated with a higher risk of developing a clot. It is important to have a hematologist advise on how significant this is for your particular clinical situation.

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Doctor answers about:

Factor 8 deficiency

A member asked:

What are the tests for factor viii deficiency?

A member asked:

What sort of disorder is factor viii deficiency?

A member asked:

What are the symptoms of factor viii deficiency?

A member asked:

What is a successful cure of hemophilia(factor viii deficiency).?

A member asked:

Is it possible to have a factor viii deficiency and not have actual hemophilia?

A member asked:

What is the treatment for factor viii deficiency?

A member asked:

Can you tell me if someone is heterozygous w/ the hemophilia gene, is it possible for them to still have factor viii deficiency?

A member asked:

What are two blood abnormalities from factor 8?

A member asked:

Would someone with antiphospholipid syndrome have an increase of factor 8?

A member asked:

What does a 162 level of factor 8 mean? lab where tested said normal range was 50-150. please advise.

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