Question 1

what leads to increased erythropoiesis?

Accepted Answer

Excercise and tumors: Erythropoiesis is  the process by which red blood cells (erythrocytes) are produced. It is stimulated by decreased O2 in circulation, which is detected by the kidneys, which then secrete the hormone erythropoietin. This hormone  then  stimulates proliferation and differentiation of red cells in the marrow. In certain diseases like kidney cancer, erythropoiesis also occurs outside the marrow.

Question 2

hypercellular marrow,increased trilineage hematopoiesis,reactive lymphoplasmacytosis, erythropoiesis normoblastic and decreased. myeloblasts not increased megakaryocytes increased, include young forms

Accepted Answer

Marrow confusion: Complex because the answer is dependent on the hematologists total examination and not just a marrow. There is a difference between dysmorphic cells and immature forms so no diagnosis can be made from your comments. Stick with the hematologist or concologist.

Question 3

help can chronic bleeding ulcer lead to increased erythropoiesis?

Accepted Answer

Erythropoiesis: Any form of blood loss will cause your body to work to create more blood cells to replenish the loss.  This process is called erythropoiesis.  If the bleeding is significant enough or has been going on long enough, it is possible to become iron deficient.  Iron deficiency is commonly caused by using up iron stores for red blood cell production but can also be caused by nutritional deficiency.

Question 4

what blood tests or any other tests are done to diagnose erythropoietic protoporphyria? is genetic test available, and if yes, where? thanks.

Accepted Answer

Protoporphyria: See below.

http://www.porphyriafoundation.com/about-porphyria/types-of-porphyria/EPP-and-XLP

Also I noted you mentioned about BP variability in position have doctors considered the diagnosis of POTS(, postural orthostatic hypotension) and other autonomic issues.

https://rarediseases.info.nih.gov/diseases/9597/postural-orthostatic-tachycardia-syndrome

Question 5

does testosterone deficiency cause anemia and reduced responsiveness to erythropoiesis-stimulating agents?

Accepted Answer

Anemia: Are you sure you have testosterone deficiency? If so is there a reason why your doctor is not checking this for you and prescribing?
Anemia is a separate problem that needs attention but testosterone replacement is very likely to increase your blood count over time.

Question 6

what's  porphyria?

Accepted Answer

Disease family: Maybe 1 person in 1000 is born with a strong tendency to porphyria cutanea tarda and some forms of hepatitis can bring it out even in a normal person; it blisters and scars sun-exposed skin. Other porphyrias masquerade as abdominal pain, mental illness, constipation, low sodium, and chronic nerve pain -- and screening tests are often done wrong. Good luck.

Question 7

what are porphyrins?

Accepted Answer

Building blocks: Porphyrins are building block molecules which form part of heme a major component of hemoglobin, the oxygen carrying molecule in blood. 

Porphyrins are also photoreactive which means when exposed to certain wavelengths of light they can induce cell killing reactions and have been used in superficial bladder cancer by giving them IV and shining a light into the bladder which can kill cancer cells.

Question 8

how does one get porphyria?

Accepted Answer

Inherited: Typically inherited problem in the breakdown of red blood cells, in particular heme. The abdominal pain and crises can be set off by medications, alcohol, or low calorie diets. Medications that cause include but are not limited to barbiturates, anticonvulsants, estrogens, oral contraceptives, or even supplements (chromium for example).

Question 9

can men have acute porphyria?

Accepted Answer

Yes: Both men and women can have acute porphyria.  However, attacks are more common in women because of hormonal changes that occur during the menstrual cycle.

Question 10

can porphyria improvewith age?

Accepted Answer

With treatment: Since most forms of porphyria are inherited there is not a cure for them. Depending on the type, treatment can relieve symptoms and improve quality of life. Acquired porphyria can improve with removal of the triggering causes.

Get Virtual Care

For Businesses

About Us

HealthTap Online Primary Care Doctors Accepting New Patients

Doctor answers about:

Erythropoietic porphyrian

A member asked:

What leads to increased erythropoiesis?

A member asked:

Hypercellular marrow,increased trilineage hematopoiesis,reactive lymphoplasmacytosis, erythropoiesis normoblastic and decreased. myeloblasts not increased megakaryocytes increased, include young forms

A member asked:

Help can chronic bleeding ulcer lead to increased erythropoiesis?

A member asked:

What blood tests or any other tests are done to diagnose erythropoietic protoporphyria? is genetic test available, and if yes, where? thanks.

A member asked:

Does testosterone deficiency cause anemia and reduced responsiveness to erythropoiesis-stimulating agents?

A member asked:

What's porphyria?

A member asked:

What are porphyrins?

A member asked:

How does one get porphyria?

A member asked:

Can men have acute porphyria?

A member asked:

Can porphyria improvewith age?

HealthTap Online Primary Care Doctors Accepting New Patients

Telemedicine

Primary Care

Manage Your Conditions

Women's Health

Children's Health

Men's Health

Senior Health

Wellness, Prevention & Lifestyle

Sexual Health

Mental & Behavioral Health

Travel Medicine

Urgent Care

Didn't find what you're looking for?

More of what we treat

Allergies

Antibiotics

Asthma

High Blood Pressure

Prescriptions

Type 2 Diabetes

For Businesses

Company

Health Content

Join Us

Download HealthTap

Questions?