Question 1

can i lower my ige?

Accepted Answer

Yes: Treatment of atopic disease, such as atopic dermatitis or asthma, can result in lowered IgE.  The B-cells that make IgE depend on certain signals in the body to live and produce antibody.  Time, changes in environmental/food/drug exposure, medicating specific diseases can all result in decreases in both total and specific IgE levels

Question 2

what is an ige blood test?

Accepted Answer

One of the tests for: Allergy. People with allergies and parasitic infestations may have elevated ige level. All lab results need to be interpreted in the clinical context and the doctor who ordered the test is usually in the best position to do that.

Question 3

what is the cause of ige myeloma?

Accepted Answer

IgE myeloma rare: Ige myeloma is rare. Dr. Kyle recently reviewed IgD and ige myelomas -- http://www.Ncbi.Nlm.Nih.Gov/pubmed/24133829
the exact cause of myeloma is not well understood.

Question 4

what are the causes of low ige in blood?

Accepted Answer

No importance..: Except that it decreases the likelihood of having an allergic disease.

Question 5

hi i have ige reading of 3,850 is it genetic?

Accepted Answer

Can Be...: Elevated total serum IgE is seen in mainly allergic diseases like allergic rhinitis and eczema. It is also seen in some primary immunodeficiencies, parasitic and viral infections, certain inflammatory diseases, and some malignancies. Atopic conditions like allergic rhinitis and eczema definitely have a genetic component to them.

Question 6

i heard that ige is specific to peanuts. is that true?

Accepted Answer

Yes: If you are allergic to peanuts (or anything else), you have specific ige that recognizes the peanut protein (or the allergen that you are sensitive to).  So an individual may have some ige that recognizes peanuts and some that recognize dust mites.  A blood test for ige just measures the total ige level.  Specific allergy testing measures how many of the total ige are for peanuts.

Question 7

what is the function of the extra domain in ige & igm?

Accepted Answer

Trick question: Are you studying immunology? The extra domain on ige  indicates a unique role for the C2 domain in the interaction between ige and fcri. C2 reduces the off-rate of the ige/fcri, thereby resulting in a more stable complex. It is felt that the domain on igm co-contributes to the pentamic structure production.

Question 8

i have extremely high ige, any chance it's not allergies?

Accepted Answer

Yes: Very high ige can be associated with atopic dermatitis (allergic eczema) and also with uncommon immune deficiency called hyper ige syndrome--typically starts in children. Usually, it is associated with allergies.

Question 9

doc how can i stop the high level ige with which medicine?

Accepted Answer

Treatment: for isolated IgE  elevation is  debatable. But if you have symptoms from allergies, then anti-histamines help.

Question 10

can we sensitize splenocytes directly using ige antibodies?

Accepted Answer

No.: Antibodies do not sensitize splenocytes.

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Doctor answers about:

Cotton IgE

A member asked:

Can i lower my ige?

A member asked:

What is an ige blood test?

A member asked:

What is the cause of ige myeloma?

A member asked:

What are the causes of low ige in blood?

A member asked:

Hi i have ige reading of 3,850 is it genetic?

A member asked:

I heard that ige is specific to peanuts. is that true?

A member asked:

What is the function of the extra domain in ige & igm?

A member asked:

I have extremely high ige, any chance it's not allergies?

A member asked:

Doc how can i stop the high level ige with which medicine?

A member asked:

Can we sensitize splenocytes directly using ige antibodies?

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