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cause of primary lateral sclerosis

A 41-year-old member asked:
Dr. Bennett Machanic
51 years experience Neurology
Variation of ALS: Motor neuron disease or ALS presents in several variable forms, and is a disease of motor neuron degeneration in brain and spinal cord. In the primar ... Read More
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A 45-year-old member asked:
Dr. Bennett Machanic
51 years experience Neurology
Variant of ALS: Als affects motor nerve cells, but varies in presentation. Diagnosis of primary lateral sclerosis is challenging, as involves upper motor neuron cel ... Read More
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2 thanks
A 37-year-old member asked:
Dr. Bennett Machanic
51 years experience Neurology
Not unexpected: Not surprising but this may not stay unilateral, or this may be the ultimate outcome. Motor neuron disorders vary in expression, but require attentiv ... Read More
A 36-year-old male asked:
Dr. Bennett Machanic
51 years experience Neurology
Variation of ALS: Motor neuron disease or ALS presents in several variable forms, and is a disease of motor neuron degeneration in brain and spinal cord. In the primar ... Read More
A 51-year-old member asked:
Dr. Bennett Machanic
51 years experience Neurology
Yes there is: Primary lateral sclerosis is a form of lou gehrig's disease, which affects the motor neuron cell, and may involve a slow chronic course. The drug Ril ... Read More
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1 thank
A 39-year-old member asked:
Dr. Bennett Machanic
51 years experience Neurology
Would be unlikely: If motor neuron disease exists, and could be in form of primary lateral sclerosis, there will usually be some degree of EMG pathology. A fully normal ... Read More
A 60-year-old male asked:
Dr. Bennett Machanic
51 years experience Neurology
Try this: Although no cure currently, the drug Riluzole has been used to slow down the process and prevent or delay tracheostomy. Some pts might benefit from o ... Read More
A 48-year-old male asked:
Dr. Steven Giannotta
48 years experience Neurosurgery
Unlikely: Although primary lateral sclerosis can be disabling, it is no where near as bad as als. You shouldn't be thinking about that but how you can best fol ... Read More
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A 37-year-old member asked:
Dr. Bennett Machanic
51 years experience Neurology
Variable, but: Many pts succumb within 5-10 yrs at most. Others may rapidly lose function over just several months to 1 or 2 years. No magic formula, but Riluzole ... Read More
A 43-year-old member asked:
Dr. Bennett Machanic
51 years experience Neurology
See below: We really do not understand the cause, but 10% are genetic and 25% of these are associated with mutations of a gene encoding copper/zinc superoxide di ... Read More
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