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can sickle cell anemia be diagnosed with a karyotype

A 48-year-old female asked:
Dr. Ed Friedlander
43 years experience Pathology
Unlikely: You may be a sickle carrier. Even the milder sickle variants -- sickle-thal, sickle-c -- usually get noticed beforehand.
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A 45-year-old member asked:
Dr. Fareeha Siddiqui
22 years experience Hematology and Oncology
Depends: It depends on the type of sickle cell disease a patient has, and how many attacks they get in a year and how severe those attacks are.
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A 44-year-old member asked:
Dr. Liawaty Ho
22 years experience Hematology and Oncology
Yes: Certain blood work - i.e. Cbc, and a hemoglobin electrophoresis, - would need to be done to establish a diagnosis of sickle cell anemia.
A 45-year-old member asked:
Dr. Michael Benjamin
22 years experience Hematology and Oncology
In 400 words?: This sounds like homework. This is simple mendelian genetics, the old 1:2:1 ratio of outcomes if two carriers mate. So if two sickle carriers mate, ... Read More
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A 48-year-old member asked:
Dr. Muaiad Kittaneh
19 years experience Addiction Medicine
In general: 50% of patients with sickle cell anemia survive beyond the 5th decade. Early mortality is high among patients whose disease is symptomatic. A high lev ... Read More
A 51-year-old member asked:
Dr. Joseph Torkildson
38 years experience Pediatric Hematology and Oncology
No: 1. All "black guys" don't have sickle cell anemia. 2. Sickle cell anemia is not contagious, it is caused by mutation in a gene that is not transfer ... Read More
A 30-year-old member asked:
Dr. Kate Tulenko
Specializes in Pediatrics
Joy, stress, meaning: How wonderful! recent developments have allowed people with sickle cell to live longer, more full, and less painful lives.However, they still have to ... Read More
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A 41-year-old member asked:
Dr. Steven Ginsberg
36 years experience Hematology and Oncology
Varies widely: There is no easy answer. The disease can be very different in different people, and there are variants of sickle cell anemia that behave very differen ... Read More
A 51-year-old female asked:
Dr. Robert Kwok
32 years experience Pediatrics
Check with Heme Dr.: Hematology doctors who takes care of the sickle problems have guidelines on cold medications that are ok to use. Some doctors recommend not using tyle ... Read More
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A 50-year-old member asked:
Dr. Ira Salafsky
55 years experience Clinical Genetics
Late teens: Carrier testing should only be done in persons who can give intelligent informed consent. Young children should not be tested. Older teens who can gi ... Read More
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