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Can I take allegra and benadryl together

A 32-year-old member asked:
Dr. Michael Zacharisen
Allergy and Immunology 33 years experience
Yes, but why: Allegra (fexofenadine) and Benadryl (diphenhydramine) are both antihistamines. Allegra doesn't cross into the brain, so no sedation. Benadryl common... Read More
Dr. Nayla Mumneh
Allergy and Immunology 29 years experience
Maybe: Depending on what you are treating, i would space them out, take Allegra in the morning and Benadryl (diphenhydramine) at night. Not sure what you are... Read More
Dr. Michael Zacharisen
Allergy and Immunology 33 years experience
2 antihistamines: At usual doses, there should not be significant side effects from taking these 2 antihistamines together. If a person is needing this much for relief... Read More

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A 25-year-old female asked:
Dr. John Feola
Internal Medicine 31 years experience
ANTIHISTAMINES: Both allegra and benadryl (diphenhydramine) are Anti-hitamines, while there is no contraindication , there effects may be additive. Monitor for excess... Read More
A 30-year-old member asked:
Dr. Lawrence Wasser
Specializes in Pediatrics
Not much: They are both antihistamines and would reduce allergic symptoms. The Benadryl (diphenhydramine) might make him/her a bit sleepy.
A 59-year-old female asked:
Dr. Al Hegab
Dr. Al Hegabanswered
Allergy and Immunology 40 years experience
Better not together: One or the other, space them out if you have to take both, but under doctor's supervision
A 59-year-old female asked:
Dr. Bruce Jacobs
Specializes in Family Medicine
No, you should: not mix antihistamines. Pick one or the other and stay with it
A 19-year-old female asked:
Dr. Kristin Sokol
Allergy and Immunology 12 years experience
Yes, but...: 19 yo female taking nasacort, allegra-D and benadryl (diphenhydramine) all together. Yes, it is safe to take these together. For allergies, often a na... Read More
A 26-year-old male asked:
Dr. Cody Mead
Family Medicine 12 years experience
Yes: You will be ok, but I would suggest talking to your doctor if you are needing that much antihistamine to feel good. There may be other medications th... Read More
A 40-year-old female asked:
Dr. John Chiu
Allergy and Immunology 57 years experience
No: It is not a good idea to take decongestant when you have hypertension. Consider an otc nasal steroid to see if it helps (may take a few days). If not... Read More
A 45-year-old member asked:
Dr. John Norvell
Allergy and Immunology 21 years experience
Yes: You can take them together. If you are sensitive to the sedating effects of antihistamines, you should not take them at the same time. It would be b... Read More
A 33-year-old member asked:
Dr. John Chiu
Allergy and Immunology 57 years experience
Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness ( the latter much less common if ... Read More

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