A 52-year-old member asked:
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Can i take Benadryl (diphenhydramine) with allegra?

1 doctor answer
Dr. John Norvell
20 years experience in Allergy and Immunology
Yes: You can take them together. If you are sensitive to the sedating effects of antihistamines, you should not take them at the same time. It would be better to take Allegra in the morning or afternoon and then Benadryl (diphenhydramine) in the evening before bed. However, if you don't feel sleepy after taking antihistamines, it would not be harmful to take them together.
Answered on Sep 5, 2018
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Related questions:

A 39-year-old member asked:
Dr. Michael Zacharisen
32 years experience in Allergy and Immunology
Yes, but why: Allegra (fexofenadine) and Benadryl (diphenhydramine) are both antihistamines. Allegra doesn't cross into the brain, so no sedation. Benadryl common ... Read More
5
5 thanks
A 49-year-old member asked:
Dr. Michael Zacharisen
32 years experience in Allergy and Immunology
2 antihistamines: At usual doses, there should not be significant side effects from taking these 2 antihistamines together. If a person is needing this much for relief ... Read More
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A 37-year-old member asked:
Dr. Lawrence Wasser
Specializes in Pediatrics
Not much: They are both antihistamines and would reduce allergic symptoms. The Benadryl (diphenhydramine) might make him/her a bit sleepy.
2
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A 60-year-old male asked:
Dr. Richard Bensinger
51 years experience in Ophthalmology
Yes: Both are effective anti-allergic medications. The major difference is that Allegra has much less tendency to cause sleep, while Benadryl (diphenhydra ... Read More

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