Question 1

at what rate does acetaminophen damage liver?

Accepted Answer

Tylenol (acetaminophen) Toxicity: For average healthy adult, daily dose should not exceed 4 grams. Toxicity can be nausea, vomiting, sweating in first 24 hours, then right upper quadrant or flank pain due to liver or kidney damage, then after few days there will be multiple organ damage, sepsis, cerebral edema & death. Damage from toxicity is prominent within 1 week if used in excess.

Question 2

what are some possible liver issues due to acetaminophen?

Accepted Answer

Tylenol (acetaminophen): If toxicity occurs, liver necrosis & damage can result.

Question 3

how probable is it that i damaged my liver with acetaminophen?

Accepted Answer

Liver: Blood work with liver function tests can clarify that.

Question 4

how much acetaminophen one can take without damaging the liver?

Accepted Answer

2,000 mgs a day: No more than this amount per 24 hrs seems to be safe. However, if you are taking multiple meds that are cleared by the liver, especially alcohol, even 2, 000 mgs a day may be potentially toxic.

Question 5

how many acetaminophen can you take without your liver shutting down?

Accepted Answer

3 Grams a day: It is recommended not to take more than 3 grams a day.  Avoid other hepatotoxic meds and alcohol while taking more than a gram a day of acetaminophen.

Question 6

how much acetaminophen can you take before severely injuring your liver?

Accepted Answer

Acetaminophen : The current maximum total dose over 24 hours is 4 grams (4, 000mg).  There is the likelihood that this may be reduced to 3 grams (3, 000 mg) in the near future.

Question 7

please advise! how much acetaminophen can you take without severely injuring your liver?

Accepted Answer

Up to 3000mg/day: Take no more than 3, 000 mg daily and you will be fine.

Question 8

how many acetaminophen would cause liver damage?

Accepted Answer

Eight plus: Most Acetaminophen pills are 500 mg. The generally accepted rule of thumb is that more than 4 grams (4000 mg) is likely to injure the liver.  Thus a person should not exceed eight Acetaminophen pills per day.  Less is even better.

Question 9

why is tylenol (acetaminophen) so damaging to the liver?

Accepted Answer

Over-dose -  NAPQI: Tylenol (acetaminophen) is metabolized by the liver with a by product called n-acetyl-p-benzoquinoneimine (napqi). Napqi damages hepatocytes (liver cells). If you take an over-dose of tylenol (acetaminophen) there is too much napqi to safely remove through urine. The napqi damages the liver.

Question 10

can you tell me how tylenol (acetaminophen) damage your liver?

Accepted Answer

Sure: The liver breaks down most of the drug into safe components. However, a small amount of Tylenol (acetaminophen) is metabolized into a harmful by-product called NAPQI (N-acetyl-p-benzoquinoneimine). When Tylenol (acetaminophen) is taken in normal doses, your body can quickly remove this toxic by-product in the urine. However, when the liver needs to metabolize a large amount of tylenol, (acetaminophen) NAPQI is overproduced and damages the liver

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Doctor answers about:

Acetaminophen and your liver

A member asked:

At what rate does acetaminophen damage liver?

A member asked:

What are some possible liver issues due to acetaminophen?

A member asked:

How probable is it that i damaged my liver with acetaminophen?

A member asked:

How much acetaminophen one can take without damaging the liver?

A member asked:

How many acetaminophen can you take without your liver shutting down?

A member asked:

How much acetaminophen can you take before severely injuring your liver?

A member asked:

Please advise! how much acetaminophen can you take without severely injuring your liver?

A member asked:

How many acetaminophen would cause liver damage?

A member asked:

Why is tylenol (acetaminophen) so damaging to the liver?

A member asked:

Can you tell me how tylenol (acetaminophen) damage your liver?

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