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HLA b27

HLA b27

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Hla = human leukocyte antigen. Important in recognition of self and not self. Different proteins (antigens) for different people. B is one of the loci, and hlab27 has been associated with predisposition to immunologic rheumatologic diseases, especially ankylosing spondylitis.

Dr. Michael Dugan reviewed this

Specializes in Hematology

Tests for

Ankylosing spondylitis
Condition

Related questions

A 36-year old male asked:

Hla b27+ve can be negitive?

1 doctor answer • 1 doctor weighed in

A 36-year old asked:

Hla b27 is itcurable or not ?

2 doctor answers • 4 doctors weighed in

A 40-year old asked:

Is hla b27 testing a very common procedure?

2 doctor answers • 6 doctors weighed in

A 28-year old male asked:

What is the definition or description of: hla b27?

2 doctor answers • 3 doctors weighed in

A 46-year old asked:

Hla-b27, bloodtest, what does it mean? What can be done?

1 doctor answer • 1 doctor weighed in

A 17-year old female asked:

Positive for hla-b27.This procedure rules out the b27:06 & 27:09 alleles which lit suggests arent associated w/ spondyloarthropathies.What this mean?

1 doctor answer • 1 doctor weighed in

A 43-year old asked:

What type of doctor can order a hla b27?

2 doctor answers • 9 doctors weighed in

A member asked:

Is hla b27 present in patients with als?

2 doctor answers • 2 doctors weighed in

A 27-year old male asked:

Why would my doctor be testing my hla-b27 gene?

1 doctor answer • 1 doctor weighed in

A 33-year old male asked:

If RF, anti CCP, HLA B27 is negative and ANA is positive what diseases can be suspected?

1 doctor answer • 2 doctors weighed in

A 17-year old female asked:

What does it mean if i'm hla-b27 positive? I have severe hip pain- does it have to do with this?

1 doctor answer • 1 doctor weighed in

A 32-year old female asked:

Had 2 blood tests for hla b27. 1st test came back positive; 2nd test (pcr) came back negative. What would be the difference between the two tests?

1 doctor answer • 2 doctors weighed in

A 32-year old female asked:

If blood test by PCR was negative for hla b27, does this mean i definitely don't have it? (one other blood test was positive; not sure of the type).

1 doctor answer • 2 doctors weighed in

A 50-year old asked:

What to do if i'm suffereing with hla b27, having a problem , back joint pain problem.?

1 doctor answer • 4 doctors weighed in

A 35-year old asked:

What do you suggest if i'm suffereing with hla b27, having a problem , back joint pain problem.?

1 doctor answer • 1 doctor weighed in

A 41-year old female asked:

I have IGA deficiency and get sick a lot . When sound I get my kids tested for it and yes they all have HLA-B27. ?

1 doctor answer • 1 doctor weighed in

A 45-year old female asked:

Can one have spondilytis without HLA-B27? Have been tested neg. Rheumy thinks it is anyway. Women45, healthy/active. No inflam on blood test yet edema

2 doctor answers • 5 doctors weighed in

A 32-year old female asked:

For blood test for hla b27 -- what is the difference between the standard test and the PCR blood test?

1 doctor answer • 1 doctor weighed in

A 45-year old asked:

What do you advise if I'm suffering with severe pain in my hip araes for last 5yrs, have hla b27 positive. MRI ws ok. pl advice?

1 doctor answer • 1 doctor weighed in

A 25-year old male asked:

If both parents are HLA-B27+ would that guarantee all offspring to have the gene? If so would only 1 positive parent make it a 50% chance?

1 doctor answer • 3 doctors weighed in

A 32-year old female asked:

Few cases of iritis. Had hla-b27 blood test done. One was positive, one was negative (by pcr). Since PCR is most sensitive, does this mean i'm clear?

1 doctor answer • 1 doctor weighed in

A 51-year old male asked:

Can my Doctor organise a HLA B27 blood test, are would it be a rheumatologist that would organise the blood test?

2 doctor answers • 2 doctors weighed in

A 33-year old male asked:

Ra, hla b27, anti ccp, ana: -ve (cut off rate 1.117, sample rate 0.198), anti-dsdna: -ve (cut off 1.501, sample:0.536). What might be causing my pain?

1 doctor answer • 1 doctor weighed in

A 47-year old male asked:

I had uveitis hla b27 disorder. It flares up once in a year. I have no specific symptoms of rheumatic arthrits. How to rule out sle and auto immune ?

3 doctor answers • 10 doctors weighed in

A 47-year old male asked:

Chronic inflammatory back pain onset age 15, chronic acute iritis, chronic fatigue are some symptoms and I am positive for hla-b27. Diagnosis? Thanks

2 doctor answers • 2 doctors weighed in

A 36-year old female asked:

Why do I have widespread OA at age 36? Mom has aggressive OA/spinal issues. I do not have HLA-B27 gene. Will I be like mom? Have cerv. spondylosis too

1 doctor answer • 2 doctors weighed in

A 40-year old female asked:

Good day I have recently tested positive for HLA-B27 after anterior uveitis Concern is persistant dull aching pain on the right side of my head. On going about 2 years. Persistant tiredness, headaches.

1 doctor answer • 1 doctor weighed in

A 49-year old female asked:

I had a positive HLA B27, positive ANA, positive SM anitobody, and a positive RNP. and Raynauds, is this likely Lupus?

2 doctor answers • 5 doctors weighed in

A 22-year old female asked:

My vit D3 level is 73.7. Hla-b27 negative I have severe joint pains nd it is neither arthritis. What could be the reason for severe pains. ?

1 doctor answer • 1 doctor weighed in

A 25-year old male asked:

Is the test for HLA-B27 gene a simple YES/NO? Remember my rheumatologist saying "highly elevated". Perhaps inflammation markers or referring to gene?

3 doctor answers • 4 doctors weighed in

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