Could i be pregnant i am on the depro shot, and these days i am more tired, have more frequent head asches, and my breasts are more sore, tender?

Always possible: Contraceptives are proved to be the best and safe , in preventing pregnancy , but has 1 % failure rate per yea. Get a pregnancy test done and speak to your doctor.

If using: The shot regularly, it's not pregnancy. Take a test if concerned. Sleeping at night? Anxiety or mood issues? Grinding teeth at night? If so explore these with your doc. Good luck.