Can losing weight make a vagina loose?

Not really: Losing weight can make all skin appear more loose as the fat cells shrink. However, this will only affect the outter area of the vagina (labia) and not the internal muscles of the vaginal wall . Also, you are unlikely to see any difference unless the weight loss is very significant (100lbs) kegel exercises can strengthen these muscles making the vagina tighter as the muscles thicken.