A member asked:

Chronic lymphoblastic leukemia: is it autosomal or sex linked?

4 doctors weighed in across 2 answers
Dr. Michael Engel answered

Specializes in Pediatric Hematology and Oncology

Neither, or both ...: This is surprisingly complex. While there are data suggesting at least a subset of cll having a familial quality (eg., clustering and vertical transmission features, etc.), there are no genes whose dysfunction are definitively correlated with cll. Atm and bcl6 are candidates, but a causal connection is far from made. Data from cgh suggest both autosomal and x-linked loci possible. Stay tuned.

Answered 8/18/2013

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Dr. Agos Luca answered

See below...: Chronic lymphoblastic leukemia does not exist. It's either chronic lymphocytic leukemia or acute lymphoblastic leukemia. None demonstrates autosomal or sex-linked transmission, at least not conclusively proven yet.

Answered 11/11/2015

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