A member asked:

Will the immune memory for high risk hpv disappear after about 20 years?

2 doctors weighed in across 2 answers
Dr. Hunter Handsfield answered

Specializes in Infectious Disease

Usually much faster -- typically a couple of years. However, HPV DNA may persist, with a potential for reactivation many years later. But the exact frequency at various intervals isn't known (i.e. 5 vs 10, 20, or 30+ years).

Answered 9/16/2021

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A history of "high risk" strains of HPV should require annual pap smears, as HPV can resurface at any time. Slow acquisition of immune status has been reported , but it is unknown about how long sustained "immunity" may last.

Answered 9/16/2021

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