If you have sex wednesday evening(9:50) took postino pill thursday evening(8:40) and the second one friday morning(9:00)...will it work ?

Usually effective: Plan B, Postinor 2, and other brands of emergency contraceptive pills can alter the menstrual cycle bleeding for the cycle in which Plan B or Postinor 2 was taken, and sometimes the next month's cycle too. One should be sure to check a home pregnancy test about 3 weeks after sex, because emergency contraceptive pills work most of the time, but not all the time.