What if my butthole still is a little irritated after the 7th dose of monistat 7 is done and took fluconazole already to before starting monistat 7?

Irritation: It is unlikely the the soreness is from a fungal infection and thus you will likely need a different type of treatment. Have you tried sitting in a warm bath a couple of times a day? One also needs to find out the cause for the irritation and thus a consult with your doctor may be needed (get a 2nd opinion if your PCP can't help you).