It's possible that 1 birth control pill cause depression?

It can: Birth control can cause depression and anxiety in some women. It is important to keep track of your moods and communicate these issues with your doctor. There might be some other alternatives available that have less of a risk.

Agree w Dr Howell: Let your gynecologist know if consistent use of your oral contraceptive is continuing to cause depressed mood. In that situation, changing the oral contraceptive may be in order.