Can side effects of depo come at different times? my 3rd shot 2/9. had sex 2/12. been cramping, was nauseous one night, discharge from breast. - test

Yes: Side effect of depo-provera, like most drugs, can occur at different times. You can experience a side effect of depo-provera that you have not experienced previously, at any time. Also, you may have side effects that come and go. The symptoms you describe could be side effects of depo-provera, or may be a sign of something else. If you have had unprotected sex, you should be tested for STDs.