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A 28-year-old male asked:

Please describe the medication: estradiol transdermal system?

2 doctor answers2 doctors weighed in
Dr. Michael Dansie
Family Medicine 17 years experience
Estradiol Patch: The Estradiol transdermal system, is designed to release Estradiol continuously upon application to intact skin.
Dr. J. Lawrence Dohan
Dermatology 58 years experience
Estrogen: May be usefull early in menopause when there is no uterus. Absorption through the skin is much more effective & safer compared to oral estrogen. Oral goes through the liver which turns out to be a problem. Natural estrogen out of the ovarian vein goes to the vena cava rather than the portal system. Without Progesterone it will cause endometrial hyperplasia which is not a problem if there is no ute.
Last updated Sep 29, 2014
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