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The Colony, TX
A 30-year-old female asked:

last mens was 10/29-11/2 w/a lupron (leuprolide) injection on 10/30. started having vag bleeding w/ bad pelvic pain today, normal w/ lupron (leuprolide)? making appt tues.

2 doctor answers4 doctors weighed in
Dr. Enrique Infante
Obstetrics and Gynecology 24 years experience
Yes : Lupron (leuprolide) will cause you pain shortly after it being given. This will resolve . However, you might start to experience hot flashes or night sweats if you we're not given add back therapy ( low dose hormones). . Pelvic pain should improve after some time - it varies per pt.
Dr. Michael Seikel
Obstetrics and Gynecology 45 years experience
Yes: Pelvic pain often gets worse the first two weeks after lupron (leuprolide). This is due to an increase in estrogen from a transient increase in pituitary fsh. This can cause vaginal bleeding also. After two weeks the fsh and estrogen level markedly drop and your pain and abnormal bleeding should improve.

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