Is a a sex change operation safe?

Yes by skilled MD: Ys, this is safe when performed by a skilled and experienced surgeon but risks do exist for any surgery.

As safe as surgeon: No surgeon is perfect, and no operation is foolproof or risk-free. Carefully-performed surgery, regardless of the kind of operation, by a skilled surgeon experienced in the procedure requested, is safe, but not guaranteed. Transgender surgery carries no specific risks, but there are fewer well-trained and experienced surgeons who do these kinds of operations. Research your surgeon carefully!