Is it possible for a male to avoid pre ejaculate fluid?

Some go for years: Unfortunately many men go on for many months w/o ejaculation, especially older ones with illnesses such as advanced diabetes, morbid obesity, heart disease, stroke victims, severe depression where desires for relation is not there and thus need for ejaculation is virtually none existent, thus no pre-ejaculation/ejaculation all together. So, many go w/o this pleasure for long periods of time.