Can an epipen (epinephrine) save you from the effects of date rape drugs?

Unfortunately, no: Epipens (epinephrine) can reverse life-threatening allergic reactions, not counter the pharmacological effects of drugs. Certain foods, stinging/biting insects, medications, and latex can set off allergic reactions -- including hives, itching, flushing, and swelling of the lips, tongue, and roof of mouth; throat & chest tightness, etc. Date rape drugs cause entirely different effects -- unless you're allergic.