Are there side effects from having a testicle removed?

Some: It really depends on the reason for removal. If for injury or failure to descend probably none. Fertility may be minimally affected if at all. If for cancer, there is a likely need for further chemotherapy and/or radiation. These may affect fertility significantly. Your doctor is the best source of information in your particular case. Thanks for trusting HealthTap!

Yes, but: For the most part there are no noticeable side effects except physical, however some men can suffer from fertility and hormonal issues. On the other hand if removal of one testicle is medically necessary then certainly benefits overweight the risks. One should discuss this in detail with the surgeon before giving the permission to have it done!

There can be: As removing a testicle can affect fertility and hormonal issues - it can lead to hypogonadism or low testosterone(which can affect libido, muscle mass, energy levels, etc). But the possible adverse effects are weighed against the reasons for needing an orchiectomy(testicle removal).