A member asked:

I take oxycodone daily for back pain. can i take a ssri in addition for anxiety/insomnia? the oxy might help with early side effects ssri's have to.

13 doctors weighed in across 4 answers

Antidepressants: Are becoming a mainstay in the treatment of many chronic pain conditions, even when depression is not recognized as a factor. Low back pain is one of the many conditions. Mechanism not fully understood. May increase neurotransmitters in the spinal cord that reduce pain signals. They dont work immediately. Ssri and tricyclic are commonly used. Talk to your pain physician before starting any drugs.

Answered 4/20/2014

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Yes.: Yes. There is no specific contraindication to the use of an ssri in the presence of oxycodone.

Answered 10/19/2013

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Yes: Narcotics can be used with ssri's and often are useful in management of chronic pain.

Answered 10/28/2013

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Dr. Qamar Khan answered

Specializes in Pain Management

Huh?: Sure. However consider Cymbalta (duloxetine) as it is used for pain, anxiety, pain and neuropathy. If you don't have any side effects it can be helpful for all your issues.

Answered 6/24/2014

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