A member asked:

What does this mean ttg lesd than 0.1 although iga is low at 0.6, lgg was less than0.1its from 2yr old boys blood results. he jhas gastro problems too?

A doctor has provided 1 answer
Dr. Scot Lewey answered

Specializes in Gastroenterology

Unlikely celiac : If you are saying that the tissue transglutaminase IgA & igg antibodies are both low in setting of a low total serum IgA then celiac disease is unlikely though not impossible. Antgliadin igg antibody may be helpful in this scenario of low total IgA as a sensitive but not specific test . Gold standard is a duodenal biopsy. Hla dq2 & dq8 genetic testing can confirm or exclude genetic risk.

Answered 2/20/2015

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