When switching from 50mcg (every 72 hours) fentanyl patch to morphine sulfate er. - what dosage is equivalent? roughly. thank you :)

Great Questions: 50mcg is roughly equivalent to 120 mg a day of morphine. However, when switching most doctors will reduce by 50% because of incomplete cross tolerance.

Very roughly...: About 100mg but with this caveat: oral versus transdermal administration can be very different as well as the degree of "cross tolerance" between the two drugs. Most physicians will start you at roughly half the equivalent dose and titrate your dose up if need be to avoid potential opioid overdose.