Can whitehead disappear itself?

Yes, sometimes: a whitehead is a collection of sebum or sticky oil in an oil gland whose openening is blocked. Sometimes the plug enlarges enough to rupture through the thin skin layer. However, it often ruptures more internally which causes inflammation, which is a red Paulette or pimple. Retin A (tretinoin) type products help to exfoliate the skin and helpful for those with acne with mostly comedones.