What is your opinion on taking st.john's wort?

They say it help: Especially in europe, they use for the treatment of depression.

Mild depression: Not very effective in forms of severe depression. However , it may be effective in mild forms of depressions or adjustment disorders.

Cannot monitor: It can be very effective for some individuals and has been used in europe for a long time for depression. In us it is not monitored, so you cannot know if you get the correct part of the plant or concentration desired for treatment. So, you cannot rely on consistent efficacy. It interacts with other meds. It is as risky as an ssri. Careful!

Mild: For mild depression it has shown some benefit. For moderate to severe not so much.

St. John: Fairly decent alternative to antidepressants if patient chooses not to take the other medications. Same for same. However, these are more expensive & should not be combined with the others.

Seems quite good: Different studies have given different results. You'll need to find the right dose for yourself. Remember it can cause paresthesias and is a photosensitizer.

Depression: "A 2009 systematic review of 29 international studies suggested that St. John’s wort may be better than a placebo (an inactive substance that appears identical to the study substance) and as effective as standard prescription antidepressants for major depression of mild to moderate severity." REF: https://nccih.nih.gov/health/stjohnswort/sjw-and-depression.htm. However, many studies are from