No 21OH-ase defect: 17 hydroxyprogesterone screens for a congenital condition, congenital adrenal hypertrophy (cah) which can lead to abnormalities of normal cortisol production and excessive adrenal male hormone production. These can present at birth, in childhood, adolescence, or adulthood depending on the nature and severity of the defect. The sensitivity of the baseline test can be increased with acth stimulation.
Answered 1/22/2021
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