A member asked:

What are the other possible reasons why creatinine in the blood increases? too much exercise? please explain. thank you.

4 doctors weighed in across 3 answers

Muscle / Kidney: There is no such thing as "too much exercise." if your creatinine is high because you're a bodybuilder (as high as 2.0 isn't unknown), good for you. If it is high because your kidneys are working poorly, it's your heads-up.

Answered 9/11/2013

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Several reasons.: Ususally due to reduced kidney function with retention of creatinine. Since it comes from muscle metabolism, creatinine can rise from serious muscle damage in which case muscle breaks down and could overwhelm the kidneys ability to excrete it.

Answered 4/24/2015

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Dr. Jimmy Bowen answered

Specializes in Physical Medicine and Rehabilitation

Creatinine: Increased lean mass with elevate the amount of creatinine seen on routine labs in people that exercise. Also anything that effects the effective filtration of the kidneys may be indicated by elevation of the blood creatinine. Examples could be the use of anti-inflammatory medications.

Answered 9/19/2013

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