A member asked:

Taking zoloft (sertraline) 25mg for 4 days, already feel extremely tired, numb, zombie like. can these side effects happen in only 4 days? thought it took weeks

6 doctors weighed in across 2 answers
Dr. Heidi Fowler answered

Specializes in Psychiatry

Some side effects: Can occur very quickly. However it can take 2 to 6 weeks to get therapeutic effect when on the optimum dose.

Answered 8/19/2020

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Yes.: It is possible to experience sedating or activating side effects in the first few days after taking an ssri. Usually, the effects wear off after a few days. If you continue to experience fatigue and numbness, speak with your medical provider about possibly changing to a different med.

Answered 9/13/2013

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