Does smoking weed interfere with amoxicillin?

Not sure : Studies have not been done on drug interactions with whst has been and still i'd an illegal drug in many places. Marinol contains the active ingredient of marijuana and is safe with Amoxicillin so it is probably safe.

It depends: What kind of illness do you have? As you know, marijuana is not pure thc. Marijuana will have a plethora of chemicals therein which may result in interactions with pharmaceuticals. Although there does not appear to be a life threatening interaction, the efficacy of Amoxicillin may well be reduced. If you have a respiratory infection, inhaling marijuana would not be helpful.