Can you take claritan during the day and nyquil at night?

Claritin (loratadine): Claritin (loratadine) is a non/sedating antihistamine, which is a longer acting drug. The usual dosing in only one a day. Nyquil has antihistamine in it, too, but it's an older one and will make most people drowsy. By taking Claritin (loratadine) in the morning and nyquil at night, you are getting more antihistamine than is recommended. Better to use a shooter acting non-sedating antihistamine like allegra.