A member asked:

Why do we give antiestrogen drugs to those who have breast cancer ?

4 doctors weighed in across 2 answers

Cancer needs estroge: Some breast cancer need estrogen to grow and their growth can be retarded by anti-estrogenic drugs.

Answered 4/8/2013

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Tumor cell: Receptors: are not on all tumors, and are checked for estrogen (er); Progesterone (pr) and now her-2-neu. If er and pr +, anti-estrogens are of some benefit. They cause tumor cells to stop dividing, and tumors to shrink. They are variable in ductal cancers, but very commonly positive in lobular carcinoma.

Answered 6/30/2014

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