Up to five days: Since it could take Effexor (venlafaxine) up to five or more days to clear you blood stream, the swelling could persist during that time. If severe , call your family doc for an antihistamine recommendation or try one over the counter, like Benadryl or loratidine. If it is severe, a short burst of steroids could be tried. L.
Answered 12/25/2015
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