A member asked:

U1rnp antibody what does it do?

A doctor has provided 1 answer
Dr. Corey Clay answered

Specializes in Allergy and Immunology

Used for diagnosis: of mixed connective tissue disease (generally scleroderma with lupus overlap and muscle inflammation) for which it is fairly specific (accurate). The action of the antibody is not well characterized and probably less important than its use for diagnostic purpose (we know it binds to a protein for RNA building). In patients with anti-centromere Ab+ scleroderma, it portends kidney complications.

Answered 3/9/2015

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