A member asked:

Help please! is celiac disease autosomal or sex-linked?

A doctor has provided 1 answer
Dr. Michael P Vaughn answered

Specializes in Allergy and Immunology

Celiac Disease: Celiac disease (cd) may have a higher prevalence in females but sex-linked genetic transmission has not been determined. The immune response genes are autosomal and there has been some linkage with certain genetic alleles hla-dq2 & dq8. If you do not have these alleles you will probably not get cd, but not everyone with these immune responce genes has cd. 30% of caucasions have dq2.

Answered 2/24/2018

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