Scleroderma: Scleroderma is a disease of the connective tissue featuring skin thickening, that can involve scarring, blood vessel problems, varying degrees of inflammation, and is associated with an overactive immune system.
Answered 8/20/2013
4.9k views
See below: Besides skin being tight and hard---an early sign is the loss of skin wrinkles and lines.
Answered 8/20/2013
4.9k views
Skin: Changes are not immediate. Any time this diagnosis comes up your should have three blood tests: a sedimentation rate, and ANA test and a scl-70 (topoisomerase) antoibody. See also a rheumatologist. Othere tests may be in place the specialist will guide you! do not delay!
Answered 4/30/2015
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