"Pop" & real science: This stands for hypothalamic pituitary adrenal axis. The physiology of these three structures and how they interact is complicated and not altogether understood, but it is very much bound up with emotions and feelings of being sick or healthy. There's a school of semi-independent medical thought that encourages people to self-diagnose "hpa axis disease". Could discuss with your personal doctor.
Answered 8/10/2013
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