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A 34-year-old member asked:

How come all down syndrome children have the same facial features?

2 doctor answers7 doctors weighed in
Dr. James Ferguson
Pediatrics 46 years experience
Chromosome influence: The size & shape of the skull & facial features of Down syndrome patients is heavily influenced bu the effect of the extra chromosome present in every cell of the body.The same goes for eyes, hands & feet all of which require a lot of decoding during formation to produce the structures. Many other chromosome defects produce some common features to those born with the abnormality.
Dr. William Singer
Pediatric Neurology 51 years experience
Chromosomes abnormal: Down syndrome is a disorder of trisomy (3) number 21 chromosomes. As a result the facial abnormality is shared by everyone with the same extra chromosome.

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Last updated Mar 23, 2018
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