How does one comfort someone with syphilis emotionally and psycholigicallt without having them feel guilty?

Syphilis: First and this is important: people can get syphilis from skin to skin contact, from saliva during kissing and then of course through exposure to infected semen, blood or vaginal fluids. It is normal to be embarrassed, but in many cases there is nothing to be ashamed about. The shame would be if one did not get treated and died from this infection.

Empathy: Try to listen with as much empathy as possible, meaning trying your best to understand how your friend is experiencing this difficulty. Be calm, caring, compassionate and remember empathic listening is a powerful tool to help lessen worry. Your a good friend. Best.