Many: Acid reflux from the stomach into the esophagus. Alcohol, smoking, caffiene, over eating, laying down within 2 hours of eating, all contribute to acid reflux. If you have frequent heartburn you should see your doctor for treatment and possibly a scope since frequent acid reflux leads to a barrett's esophagus which predisposes you to esophageal cancer.
Answered 5/28/2015
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